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All nuclear reactors will generate waste via activation as the materials of which they are constructed erode and become unstable under high neutron flux. I'm not pointing this out because I think it's a big deal — a few fusion advocates disingenuously tend to sell the process as if it were "100% clean." A low volume of non-recyclable waste from fusion reactors that is walk-away safe in ~100 years is doable. Let's do it. And likewise, the best comparable waste profile for fission is a two-fluid LFTR, a low volume of waste that is walk-away safe in ~300 years. Let's do it.
Why pursue both, with at least the same level of urgency? Because both could carry us indefinitely. LFTR is less complicated in theory and practice. It is closer to market. There is plenty of cross-over: LFTR's materials challenges and heat engine interface — and the necessity for waste management — are the same as they will be for commercial-scale fusion reactors. To get up to speed please see the 2006 fusion lecture by Dr. Robert Bussard on the Wiffle ball 6 plasma containment, likely the precursor to the Skunkworks approach. And see Thorium Remix 2011 which presents the case for LFTR.