Catch up on stories from the past week (and beyond) at the Slashdot story archive

 



Forgot your password?
typodupeerror
For the out-of-band Slashdot experience (mostly headlines), follow us on Twitter, or Facebook. ×
Biotech

+ - Gamers outdo computers at DNA sequence alignments->

ananyo writes: In another victory for crowdsourcing, gamers playing Phylo (http://phylo.cs.mcgill.ca/) have beaten a state-of-the-art program at aligning regions of 521 disease-associated genes form different species (http://www.nature.com/news/gamers-outdo-computers-at-matching-up-disease-genes-1.10203).
The 'multiple sequence alignment problem' refers to the difficulty of aligning roughly similar sequences of DNA in genes common to many species (http://en.wikipedia.org/wiki/Multiple_sequence_alignment). DNA sequences that are conserved across species may play an important role in the ultimate function of that particular gene. But with thousands of genomes likely to be sequenced in the next few years, sequence alignment will only become more difficult in future.
Researchers now report that players of Phylo have produced roughly 350,000 solutions to various multiple sequence alignment problems, beating the accuracy of alignments from a program in roughly 70% of the sequences they manipulated (paper http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0031362).

Link to Original Source
This discussion was created for logged-in users only, but now has been archived. No new comments can be posted.

Gamers outdo computers at DNA sequence alignments

Comments Filter:

There is no opinion so absurd that some philosopher will not express it. -- Marcus Tullius Cicero, "Ad familiares"

Working...