Want to read Slashdot from your mobile device? Point it at m.slashdot.org and keep reading!

 



Forgot your password?
typodupeerror

Slashdot videos: Now with more Slashdot!

  • View

  • Discuss

  • Share

We've improved Slashdot's video section; now you can view our video interviews, product close-ups and site visits with all the usual Slashdot options to comment, share, etc. No more walled garden! It's a work in progress -- we hope you'll check it out (Learn more about the recent updates).

×
Biotech

+ - Gene Transfer Immunizes Against Monkey HIV ->

Submitted by
Al
Al writes "Researchers at the University of Pennsylvania have immunized monkeys against the simian immunodeficiency virus (SIV), the animal model that is closest to HIV. They did so by shuttling a gene into the monkeys' muscles, making the muscle cells produce antibody-like molecules that work against SIV. With both SIV and HIV, the chameleon-like mutability of the virus's surface changes so quickly that most antibodies made by the immune system are soon rendered ineffective. Philip Johnson and colleagues designed DNA sequences for two antibodies known to be effective against SIV. They used antibody-like molecules, called immunoadhesins, in which the functional part of an antibody is fused with a more stable section of another antibody. The same approach could be used to deliver antibodies that are effective against HIV, but which the body doesn't normally produce."
Link to Original Source
This discussion was created for logged-in users only, but now has been archived. No new comments can be posted.

Gene Transfer Immunizes Against Monkey HIV

Comments Filter:

One can't proceed from the informal to the formal by formal means.

Working...