JJJumper writes "CoolTechZone.com reviews Evoluent's VerticalMouse 3 mouse that's touted to be the world's most health conscious, ergonomics friendly mouse in the world. And it's vertical, too, instead of horizontal. The review states, "Unlike other mice, Evoluent's VerticalMouse 3 stands vertical to locate your hand in a handshake position, or where the arm is in 90-degrees form from the tabletop. It even has a small lip at the bottom to prevent your little finger from touching the desk. According to the company, this is the most natural position for the hand to be in and it reduces a magnitude of stress from your hand, wrist and arm. Apparently traditional mice with horizontal statures twist your lower arm and put unnecessary stress on its vital areas. We must admit that getting used to the mouse didn't take too long, even though it was slightly awkward to get used to in the beginning. After all, old habits die hard."