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Books

Amazon's eBook Math 150

Posted by Soulskill
from the there's-one-for-you-nineteen-for-me dept.
An anonymous reader writes: Amazon has waged a constant battle with publishers over the price of ebooks. They've now publicly laid out their argument and the business math behind it. "We've quantified the price elasticity of e-books from repeated measurements across many titles. For every copy an e-book would sell at $14.99, it would sell 1.74 copies if priced at $9.99. So, for example, if customers would buy 100,000 copies of a particular e-book at $14.99, then customers would buy 174,000 copies of that same e-book at $9.99. Total revenue at $14.99 would be $1,499,000. Total revenue at $9.99 is $1,738,000." They argue that capping most ebooks at $9.99 would be better for everyone, with the money split out 35% to the author, 35% to the publisher, and 30% to Amazon.

Author John Scalzi says Amazon's reasoning and assumptions are a bit suspect. He disagrees that "books are interchangeable units of entertainment, each equally as salable as the next, and that pricing is the only thing consumers react to." Scalzi also points out that Amazon asserts itself as the only revenue stream for authors, which is not remotely true. "Amazon's assumptions don't include, for example, that publishers and authors might have a legitimate reason for not wanting the gulf between eBook and physical hardcover pricing to be so large that brick and mortar retailers suffer, narrowing the number of venues into which books can sell. Killing off Amazon's competitors is good for Amazon; there's rather less of an argument that it's good for anyone else."
Medicine

The Problems With Drug Testing 115

Posted by Soulskill
from the inject-directly-into-eyeball-six-times-daily dept.
gallifreyan99 writes: Every drug you take will have been tested on people before it—but that testing process is meant to be tightly controlled, for the safety of everyone involved. Two investigations document the questionable methods used in many studies, and the lack of oversight the FDA seems to have over the process. First, drugs are increasingly being tested on homeless, destitute and mentally ill people. Second, it turns out many human trials are being run by doctors who have had their licenses revoked for drug addiction, malpractice and worse.
Science

More Quantum Strangeness: Particles Separated From Their Properties 85

Posted by Soulskill
from the superposition-of-cat-metaphors dept.
Dupple sends word of new quantum mechanical research in which a neutron is sent along a different path from one of its characteristics. First, a neutron beam is split into two parts in a neutron interferometer. Then the spins of the two beams are shifted into different directions: The upper neutron beam has a spin parallel to the neutrons’ trajectory, the spin of the lower beam points into the opposite direction. After the two beams have been recombined, only those neutrons are chosen which have a spin parallel to their direction of motion. All the others are just ignored. ... These neutrons, which are found to have a spin parallel to its direction of motion, must clearly have travelled along the upper path — only there do the neutrons have this spin state. This can be shown in the experiment. If the lower beam is sent through a filter which absorbs some of the neutrons, then the number of the neutrons with spin parallel to their trajectory stays the same. If the upper beam is sent through a filter, than the number of these neutrons is reduced.

Things get tricky when the system is used to measure where the neutron spin is located: the spin can be slightly changed using a magnetic field. When the two beams are recombined appropriately, they can amplify or cancel each other. This is exactly what can be seen in the measurement, if the magnetic field is applied at the lower beam – but that is the path which the neutrons considered in the experiment are actually never supposed to take. A magnetic field applied to the upper beam, on the other hand, does not have any effect.
Space

The Milky Way Is Much Less Massive Than Previous Thought 110

Posted by Soulskill
from the galactic-atkins dept.
schwit1 writes: New research by astronomers suggests that the Milky Way is about half as massive as previously estimated. It was thought to be roughly the same mass as Andromeda, weighing in at approximately 1.26 x 10^12 solar masses (PDF). This new research indicates its mass is around half the mass of Andromeda. "Galaxies in the Local Group are bound together by their collective gravity. As a result, while most galaxies, including those on the outskirts of the Local Group, are moving farther apart due to expansion, the galaxies in the Local Group are moving closer together because of gravity. For the first time, researchers were able to combine the available information about gravity and expansion to complete precise calculations of the masses of both the Milky Way and Andromeda. ... Andromeda had twice as much mass as the Milky Way, and in both galaxies 90 percent of the mass was made up of dark matter."
Mars

Opportunity Rover Sets Off-World Driving Record 46

Posted by Soulskill
from the rollin'-rollin'-rollin' dept.
schwit1 writes: "With a drive of 157 feet on Sunday, the Mars rover Opportunity broke the Soviet record, set by Lunokhod 2 in 1973, for the longest distance traveled by a vehicle on another planet. "If the rover can continue to operate the distance of a marathon — 26.2 miles (about 42.2 kilometers) — it will approach the next major investigation site mission scientists have dubbed "Marathon Valley." Observations from spacecraft orbiting Mars suggest several clay minerals are exposed close together at this valley site, surrounded by steep slopes where the relationships among different layers may be evident. The Russian Lunokhod 2 rover, a successor to the first Lunokhod mission in 1970, landed on Earth's moon on Jan. 15, 1973, where it drove about 24.2 miles (39 kilometers) in less than five months, according to calculations recently made using images from NASA's Lunar Reconnaissance Orbiter (LRO) cameras that reveal Lunokhod 2's tracks."
Space

Enceladus's 101 Geysers Blast From Hidden Ocean 38

Posted by Soulskill
from the say-it-don't-spray-it dept.
astroengine writes: New observations from NASA's Saturn-orbiting Cassini spacecraft have revealed at least 101 individual geysers erupting from Enceladus' crust and, through careful analysis, planetary scientists have uncovered their origin. From the cracked ice in this region, fissures blast out water vapor mixed with organic compounds as huge geysers. Associated with these geysers are surface "hotspots" but until now there has been some ambiguity as to whether the hotspots are creating the geysers or whether the geysers are creating the hotspots. "Once we had these results in hand, we knew right away heat was not causing the geysers, but vice versa," said Carolyn Porco, leader of the Cassini imaging team from the Space Science Institute in Boulder, Colo., and lead author of one of the research papers. "It also told us the geysers are not a near-surface phenomenon, but have much deeper roots." And those roots point to a large subsurface source of liquid water — adding Enceladus as one of the few tantalizing destinations for future astrobiology missions.
Medicine

UK Team Claims Breakthrough In Universal Cancer Test 63

Posted by Unknown Lamer
from the coming-to-a-patent-office-near-you dept.
An anonymous reader writes UK researchers say they've devised a simple blood test that can be used to diagnose whether people have cancer or not. The Lymphocyte Genome Sensitivity (LGS) test looks at white blood cells and measures the damage caused to their DNA when subjected to different intensities of ultraviolet light (UVA), which is known to damage DNA. The results of the empirical study show a distinction between the damage to the white blood cells from patients with cancer, with pre-cancerous conditions and from healthy patients. "Whilst the numbers of people we tested are, in epidemiological terms, quite small (208), in molecular epidemiological terms, the results are powerful," said the team's lead researcher. "We've identified significant differences between the healthy volunteers, suspected cancer patients and confirmed cancer patients of mixed ages at a statistically significant level .... This means that the possibility of these results happening by chance is 1 in 1000." The research is published online in the FASEB Journal, the U.S. Journal of the Federation of American Societies for Experimental Biology.
Medicine

Smoking Mothers May Alter the DNA of Their Children 152

Posted by Unknown Lamer
from the that-explains-the-hooves dept.
sciencehabit (1205606) writes "Pregnant women who smoke don't just harm the health of their baby—they may actually impair their child's DNA, according to new research. A genetic analysis shows that the children of mothers who smoke harbor far more chemical modifications of their genome — known as epigenetic changes — than kids of non-smoking mothers. Many of these are on genes tied to addiction and fetal development. The finding may explain why the children of smokers continue to suffer health complications later in life.
Communications

How Bird Flocks Resemble Liquid Helium 40

Posted by timothy
from the beats-speed-of-sound dept.
sciencehabit (1205606) writes "A flock of starlings flies as one, a spectacular display in which each bird flits about as if in a well-choreographed dance. Everyone seems to know exactly when and where to turn. Now, for the first time, researchers have measured how that knowledge moves through the flock—a behavior that mirrors certain quantum phenomena of liquid helium. Some of the more interesting findings: Tracking data showed that the message for a flock to turn started from a handful of birds and swept through the flock at a constant speed between 20 and 40 meters per second. That means that for a group of 400 birds, it takes just a little more than a half-second for the whole flock to turn."
Medicine

Newly Discovered Virus Widespread in Human Gut 99

Posted by timothy
from the right-under-their-noses-and-stomachs dept.
A newly discovered virus has been found by a San Diego State University team to live inside more than half of all human gut cells sampled. Exploring genetic material found in intestinal samples, the international team uncovered the CrAssphage virus. They say the virus could influence the behaviour of some of the most common bacteria in our gut. Researchers say the virus has the genetic fingerprint of a bacteriophage - a type of virus known to infect bacteria. Phages may work to control the behaviour of bacteria they infect - some make it easier for bacteria to inhabit in their environments while others allow bacteria to become more potent. [Study lead Dr. Robert] Edwards said: "In some way phages are like wolves in the wild, surrounded by hares and deer. "They are critical components of our gut ecosystems, helping control the growth of bacterial populations and allowing a diversity of species." According to the team, CrAssphage infects one of the most common types of bacteria in our guts. National Geographic gives some idea why a virus so common in our gut should have evaded discovery for so long, but at least CrAssphage finally has a Wikipedia page of its own.
NASA

Off the Florida Coast, Astronauts Train For Asteroid Mission 82

Posted by timothy
from the in-space-no-one-can-hear-you-access-facebook dept.
Space.com gives an overview of the training that four astronauts are undergoing over 9 days submerged off the coast of Florida near Key Largo. The training mission, dubbed NEEMO 18, is one step toward a proposed (mid-2020s) mission to actually visit a captured asteroid in lunar orbit. In addition to the complications of working outside their school-bus sized habitat while awkwardly suited up in a low-gravity (or at least high buoyancy) environment, their mission also includes a 10-minute communications delay, to simulate the high-latency communications with mission control that would be inevitable for an actual asteroid mission. The experiments astronauts are doing during the mission, which began Monday (July 21), range from the physical to the behavioral. For example, each of the crew members sports a sensor that records how close the crew members work with each other inside the school-bus-size habitat. ... Communications with NEEMO Mission Control is usually constant, and there is the ability to send items to and from the habitat as needed. Also living inside the habitat are two support staff who are assisting with Aquarius maintenance and systems, as required. The crew members also have Internet and phone service to talk with family and friends.
NASA

SpaceX Executive Calls For $22-25 Billion NASA Budget 114

Posted by timothy
from the only-tax-dollars-after-all dept.
MarkWhittington (1084047) writes "While participating in a panel called "The US Space Enterprise Partnership" at the NewSpace Conference that was held by the Space Frontier Foundation on Saturday, SpaceX Chief Operating Officer Gwynne Shotwell opined that NASA's budget should be raised to $22-25 billion, according to a tweet by Space Policy Online's Marcia Smith. The theory is that a lot of political rancor has taken place in the aerospace community because of the space agency's limited budget. If the budget were to be increased to pay for everything on the space wish list, the rancor will cease.

The statement represents something of a departure of the usual mutual antagonism that exists between some in the commercial space community and some at NASA. Indeed Space Politics' Jeff Foust added a tweet, "Thought: a panel at a Space Frontier Foundation conf is talking about how to increase NASA budget. Imagine that in late 90s." The Space Frontier Foundation has been a leading voice for commercializing space, sometimes at the expense of NASA programs."
Medicine

Amputee Is German Long Jump Champion 175

Posted by timothy
from the we-are-all-augmented dept.
hweimer (709734) writes "German long jumper Markus Rehm has written sports history yesterday, becoming the first disabled athlete to win a national able-bodied championship. His jump to 8.24 meters put him on the 9th place of the current season rankings and make him egligible to compete in the upcoming European championships, further sparking the debate whether his prosthetic leg provides him with an unfair advantage."
Medicine

Two South African Cancer Patients Receive 3D Printed Titanium Jaw Implants 71

Posted by timothy
from the ok-but-they-did-already-need-them dept.
jigmypig (3675225) writes "Two patients in South Africa that have had their lives and more specifically their jaws severely affected by cancer, have just received 3D printed jaw implants. The jaws were 3D printed using a laser sintering process that melts powdered titanium, one layer at a time. The process saves a ton of money, and unlike traditional manufacturing of titanium jaws, it doesn't waste any materials. Traditional manufacturing wastes up to 80% of the titanium block used in the process, whereas with 3D printing there is little to no waste at all. This new process also allows for a fully customizable solution. The models are drawn up in CAD software, and then printed out to precisely fit the patient."
Books

Nightfall: Can Kalgash Exist? 86

Posted by timothy
from the burning-questions dept.
First time accepted submitter jIyajbe (662197) writes Two researchers from the Indian Institute of Astrophysics investigate the imaginary world of Kalgash, a planetary system based on the novel 'Nightfall' (Asimov & Silverberg, 1991). From the arXiv paper: "The system consists of a planet, a moon and an astonishing six suns. The six stars cause the wider universe to be invisible to the inhabitants of the planet. The author explores the consequences of an eclipse and the resulting darkness which the Kalgash people experience for the first time. Our task is to verify if this system is feasible, from the duration of the eclipse, the 'invisibility' of the universe to the complex orbital dynamics." Their conclusion? "We have explored several aspects of Asimov's novel. We have found that the suns, especially Dovim are bright enough to blot out the stars. Kalgash 2 can eclipse Dovim for a period of 9 hours. We also tested one possible star configuration and after running some simulations, we found that the system is possible for short periods of time."
Science

Soccer Superstar Plays With Very Low Brain Activity 157

Posted by timothy
from the one-hemisphere-tied-behind-his-back dept.
jones_supa (887896) writes "Brazilian superstar Neymar's (Neymar da Silva Santos Júnior) brain activity while dancing past opponents is less than 10 per cent the level of amateur players, suggesting he plays as if on "auto-pilot", according to Japanese neurologists Eiichi Naito and Satoshi Hirose. The findings were published in the Swiss journal Frontiers in Human Neuroscience following a series of motor skills tests carried out on the 22-year-old Neymar and several other athletes in Barcelona in February this year. Three Spanish second-division footballers and two top-level swimmers were also subjected to the same tests. Researcher Naito told Japan's Mainichi Shimbun newspaper: "Reduced brain activity means less burden which allows [the player] to perform many complex movements at once. We believe this gives him the ability to execute his various shimmies." In the research paper Naito concluded that the test results "provide valuable evidence that the football brain of Neymar recruits very limited neural resources in the motor-cortical foot regions during foot movements"."
Communications

The Truth About Solar Storms 90

Posted by timothy
from the deepen-the-basement dept.
StartsWithABang (3485481) writes On Wednesday, The Washington Post ran a story about a very large solar flare two years ago that missed Earth, but not by too much. From a scientific point of view, what is it that happens when a solar flare interacts with Earth, and what are the potential dangers to both humans and humanities infrastructure? A very good overview, complete with what you can do — as both an individual and a power company — to minimize the risk and the damage when the big one comes. Unlike asteroids, these events happen every few centuries, and in our age of electronics, would now create a legitimate disaster.
Medicine

Google Looking To Define a Healthy Human 125

Posted by Soulskill
from the bet-this-one's-going-to-get-Godwinned-quick dept.
rtoz writes: Google's moonshot research division, "Google X," has started "Baseline Study," a project designed to collect anonymous genetic and molecular information from 175 people (and later thousands more) to create a complete picture of what a healthy human being should be. The blueprint will help researchers detect health problems such as heart disease and cancer far earlier, focusing medicine on prevention rather than treatment. According to Google, the information from Baseline will be anonymous, and its use will be limited to medical and health purposes. Data won't be shared with insurance companies.
NASA

SLS Project Coming Up $400 Million Short 132

Posted by Soulskill
from the opportunity-for-real-life-iron-man dept.
schwit1 writes: A GAO report finds that the Space Launch System is over budget and NASA will need an additional $400 million to complete its first orbital launch in 2017. From the article: "NASA isn't meeting its own requirements for matching cost and schedule resources with the congressional requirement to launch the first SLS in December 2017. NASA usually uses a calculation it calls the 'joint cost and schedule confidence level' to decide the odds a program will come in on time and on budget. 'NASA policy usually requires a 70 percent confidence level for a program to proceed with final design and fabrication,' the GAO report says, and the SLS is not at that level. The report adds that government programs that can't match requirements to resources 'are at increased risk of cost and schedule growth.'

In other words, the GAO says SLS is at risk of costing more than the current estimate of $12 billion to reach the first launch or taking longer to get there. Similar cost and schedule problems – although of a larger magnitude – led President Obama to cancel SLS's predecessor rocket system called Constellation shortly after taking office." The current $12 billion estimate is for the program's cost to achieve one unmanned launch. That's four times what it is costing NASA to get SpaceX, Boeing, and Sierra Nevada to build their three spaceships, all scheduled for their first manned launches before 2017.
Science

Siberian Discovery Suggests Almost All Dinosaurs Were Feathered 139

Posted by Soulskill
from the tyrannosaurus-big-bird dept.
A new study published in Science (abstract) suggests that most dinosaurs were covered with feathers. This conclusion was drawn after the discovery of fossils belonging to a 1.5-meter-long, two-legged dinosaur called Kulindadromeus zabaikalicus. "The fossils, which included six skulls and many more bones, greatly broaden the number of families of dinosaurs sporting feathers—downy, ribboned, and thin ones in this case—indicating that plumes evolved from the scales that covered earlier reptiles, probably as insulation." Its distinctiveness from earlier theropod fossil discoveries suggests that feathered dinosaurs appeared much further back in history than previously thought. Paleontologist Stephen Brusatte said, "This does mean that we can now be very confident that feathers weren't just an invention of birds and their closest relatives, but evolved much deeper in dinosaur history. I think that the common ancestor of dinosaurs probably had feathers, and that all dinosaurs had some type of feather, just like all mammals have some type of hair."

I'd rather just believe that it's done by little elves running around.

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